武漢多普樂(lè)生物醫(yī)藥有限公司
武漢市洪山區(qū)獅子山北路攬勝匯公寓樓1號(hào)樓B區(qū)619室
錢小如
19945035818 027-87215551
2881924056
(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid，分子式 C14H18O4分子量250.29Beilstein號(hào) 1384050MDL號(hào) MFCD00006846
Trolox is an antioxidant derived from water-soluble vitamin E, with oxygen quenching activity. The activity of Trolox ranges between ferulic acid and p-coumaric acid. Studies show that lipid peroxidation, cytotoxicity, and apoptosis induced by cytochrome P450 2E1 in Hep G2 cells is blocked in the presence of Trolox. It has been observed that Trolox can quench free radicals and inhibit methylmercury (MeHg)-induced reactive oxygen species (ROS) generation in C6 glial cells. In addition, Trolox has demonstrated the ability to reduce cytotoxicity of Microcystis aerμginosa and microcystin-LR in Artemia franciscana nauplii. ()-6-hydroxy -2,5,7,8- tetramethylchroman -2- carboxylic acid (Trolox) exhibits free radical scavenging and antioxidant activities.
An antioxidant derived from water-soluble vitamin E ()-6- hydroxy -2,5,7,8- tetramethylchroman -2- carboxylic acid (Trolox) has been used in the equivalent antioxidant test (TEAC) of 6-hydroxy -2,5,7,8- tetramethylchroman -2- carboxylic acid to determine different fruits.
| 危害聲明 | H302, |
| 警示性聲明 | P501,P264,P270, |
| RTECS | DJ2273000 |
| WGK | 2 |
| 產(chǎn)品名稱 | 奎諾二甲基丙烯酸酯 |
|---|---|
| 產(chǎn)品名稱 | (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid |
| 產(chǎn)品英文名稱 | (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid |
| 別名 | 水溶性維生素E;6-羥基-2,5,7,8-四甲基苯并二氫吡喃-2-甲酸,(±)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸 |
| 英文別名 | Trolox;6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid |
| CAS編號(hào) | 53188-07-1 |
| 分子式 | C14H18O4 |
| 分子量 | 250.29 |
| PubChem CID | 40634 |
| MDL號(hào) | MFCD00006846 |
| Beilstein | 1384050 |
| Reaxys-RN | 5052542 |
| 規(guī)格或純度 | 98% |
| 應(yīng)用 | An antioxidant derived from water-soluble vitamin E (±)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸（Trolox）已用于6-羥基-2,5,7,8-四甲基色滿-2-羧酸等效抗氧化檢測(cè)（TEAC）以確定不同水果物種的總抗氧化能力 |
| 備注 | 如果有可能，您盡量在同一天配置溶液，并在當(dāng)天使用完它。但是，如果您需要預(yù)先配制儲(chǔ)備溶液，我們建議您將溶液等份保存在-20°C的密封小瓶中。通常，它們最多可以使用一個(gè)月。在使用前和打開樣品瓶之前，我們建議您讓您的產(chǎn)品在室溫下平衡至少1小時(shí)。需要更多關(guān)于溶解度，用法和處理的建議嗎？請(qǐng)?jiān)L問(wèn)我們的常見(jiàn)問(wèn)題（FAQ）頁(yè)面以獲取更多詳細(xì)信息。 |
| 生化機(jī)理 | 抗氧化劑維生素E衍生物。表現(xiàn)出脂質(zhì)過(guò)氧化，DPPH°清除和HO°清除活性。經(jīng)常用作抗氧化劑標(biāo)準(zhǔn)。具有細(xì)胞滲透性和水溶性。 |
| 熔點(diǎn) | 187-189 °C |
| 敏感性 | 空氣敏感 |
| 溶解性 | Soluble in 100% ethanol (25 mg/ml), methanol, water(slightly), DMSO (~20 mg/ml), DMF (~20 mg/ml), and PBS( pH7.2) (~3 mg/ml). |
| 儲(chǔ)存溫度 | 2-8°C儲(chǔ)存,充氬, |
| 運(yùn)輸條件 | 冰袋運(yùn)輸, |
| 品牌 | 多普樂(lè) |